Wilma, who started going blind at the age of 2, belongs to Jim Shamp, Director of Public Relations for the N.C. Biotechnology Center.
RESEARCH TRIANGLE PARK, N.C. — Zoion Pharma of Durham has formed a collaboration with the French veterinary company Ceva Santé Animale to develop a treatment for eye diseases in companion animals.
The companies did not disclose financial terms of the collaboration which gives Ceva worldwide development and commercial rights to Zoion’s drug candidate ZP-1, which Zoion has been targeting as a dry-eye treatment for dogs.
Technically, it’s an epithelial sodium channel inhibitor for the treatment of veterinary ocular surface diseases involving a lack of surface hydration, such as keratoconjunctivitis sicca (KCS), commonly called dry eye.
“KCS is a disease that causes much pain and discomfort, particularly in dogs,” said Jon Alšėnas, D.V.M., president and CEO of Zoion. “If left untreated, severe cases may lead to blindness.”
Drug originally discovered by Parion Sciences
ZP-1 has successfully completed a proof-of-concept clinical trial in canine dry eye. It was originally discovered by Parion Sciences of Durham and then licensed to Zoion for veterinary use. [Read full article….]
Advance could lead to new treatments for millions afflicted with the condition
More than half of Americans over the age of 70 have cataracts, caused by clumps of proteins collecting in the eye lens. The only way to remove them is surgery, an unavailable or unaffordable option for many of the 20 million people worldwide who are blinded by the condition. Now, a new study in mice suggests eye drops made with a naturally occurring steroid could reverse cataracts by teasing apart the protein clumps.
Dry eye affects around one in 22 dogs, and can affect up to 20 per cent of at risk breeds, yet in a recent survey, nearly half of dog owners were not aware that the condition could pose a potential risk to their pet.
To help address this, Bayer Animal Health has launched an educational website (www.remend.co.uk)specifically designed to help dog owners understand more about dry eye; covering clinical signs, predisposed breeds, diagnosis and treatment, with the key message throughout encouraging owners to speak to their vet with any concerns.
The website has been launched to support Bayer’s new tear replacement product, Remend TM Dry Eye Lubricant Drops, which is intended for use as part of the management of dry eye, alongside prescription medication, after the condition has been diagnosed by a veterinary surgeon. RemendTM Dry Eye Lubricant Drops provide long-lasting lubrication for the eyes, and have the advantage that they can be applied less frequently than the majority of artificial tear supplements currently on the market. [Read full article….]
Dr Sam Long, Head of Neurology with patient, Ruby. Credit: Wyndham Weekly.
There are many parallels between the conditions suffered by both humans and pets, as they are exposed to the same environment, which means research in medical and veterinary science fields often has human implications.
Researchers at the University of Melbourne are focusing on ground-breaking research into a range of conditions suffered both by animals and humans. The research will hopefully change the way pets and humans are diagnosed and treated, and Continue reading →
Originally published January 30, 2014 at midnight, updated January 30, 2014 at midnight
Dry eye is a painful and potentially dangerous condition that occurs because of lack of tear production.
There are a number of different symptoms you can see if your dog has this issue. Common signs include pawing or rubbing at the eyes, redness, dullness of the cornea, thick discharge, sensitivity to light, swollen eyelids, squinting, ulceration of the cornea, blinking excessively and impaired vision.
In most cases, the eyes start off itchy, red and irritated, and if left untreated, they Continue reading →